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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Taglntm1Liw
targeted mutation 1, Li Li
MGI:3526077
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Taglntm1Liw/Taglntm1Liw involves: 129/Sv * C57BL/6 MGI:4459512
cx2
 		Taglntm1Liw/Tagln+
Tbx18tm1.1Mwmy/Tbx18tm1.1Mwmy 		involves: 129 * C57BL/6J MGI:5553118


Genotype
MGI:4459512
hm1
Allelic
Composition		 Taglntm1Liw/Taglntm1Liw
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Taglntm1Liw mutation (1 available); any Tagln mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:160843 )
• mice are viable and fertile




Genotype
MGI:5553118
cx2
Allelic
Composition		 Taglntm1Liw/Tagln+
Tbx18tm1.1Mwmy/Tbx18tm1.1Mwmy
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Taglntm1Liw mutation (1 available); any Tagln mutation (28 available)
Tbx18tm1.1Mwmy mutation (0 available); any Tbx18 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal vascular smooth muscle morphology ( J:203805 )
• reduced smooth muscle content and shorter overall smooth muscle coverage at birth
abnormal coronary vessel morphology ( J:203805 )
• less developed branching network of subepicardial conduit vessels
abnormal coronary artery morphology ( J:203805 )
• reduced smooth muscle content and shorter overall smooth muscle coverage at birth
• reduced overall diameter of the coronary stems and reduced branching index

muscle
abnormal vascular smooth muscle morphology ( J:203805 )
• reduced smooth muscle content and shorter overall smooth muscle coverage at birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory