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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd207tm1Mal
targeted mutation 1, Bernard Malissen
MGI:3526083
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd207tm1Mal/Cd207tm1Mal B6.129S2-Cd207tm1Mal MGI:3526433


Genotype
MGI:3526433
hm1
Allelic
Composition		 Cd207tm1Mal/Cd207tm1Mal
Genetic
Background		 B6.129S2-Cd207tm1Mal
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd207tm1Mal mutation (1 available); any Cd207 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal Langerhans cell morphology ( J:95147 )
• Langerhans cell lack Birbeck granules but capture antigen, migrate, and undergo phenotypic maturation normally and homozygous mutant mice have normal sensitivity to pathogenic bacteria

immune system
abnormal Langerhans cell morphology ( J:95147 )
• Langerhans cell lack Birbeck granules but capture antigen, migrate, and undergo phenotypic maturation normally and homozygous mutant mice have normal sensitivity to pathogenic bacteria




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory