About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptcratm1Bjf
targeted mutation 1, B J Fowlkes
MGI:3526158
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ptcratm1Bjf/Ptcra+ involves: 129X1/SvJ MGI:3805108


Genotype
MGI:3805108
ht1
Allelic
Composition		 Ptcratm1Bjf/Ptcra+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptcratm1Bjf mutation (0 available); any Ptcra mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:94338 )
• 30% fewer DN4 T cells are in S+G2/M phase of the cell cycle than in wild-type mice
decreased double-negative T cell number ( J:94338 )
• reduced 30% to 40% compared to in wild-type mice
decreased single-positive T cell number ( J:94338 )
• reduced 30% to 40% compared to in wild-type mice

hematopoietic system
abnormal T cell differentiation ( J:94338 )
• 30% fewer DN4 T cells are in S+G2/M phase of the cell cycle than in wild-type mice
decreased double-negative T cell number ( J:94338 )
• reduced 30% to 40% compared to in wild-type mice
decreased single-positive T cell number ( J:94338 )
• reduced 30% to 40% compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory