behavior/neurological
• following administration of capsaicin mice show an increased tolerance to weight application relative to wild-type controls
• however, baseline thresholds are similar to controls
|
• following administration of capsaicin mice show an prolonged latency of withdrawal from a thermal source relative to wild-type controls
• however, baseline thresholds are similar to controls
|
homeostasis/metabolism
• plasma levels of PGEM, a PGE1 and PGE2 metabolite, are about 50% lower than in wild-type controls
|