hematopoietic system
• thymocytes fail to mature beyond the double positive stage
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• no single positive T cells are seen in spleen and lymph nodes
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• antibody induced co-cross-linking of surface T cell receptors and CD4 failed to mobilize intracellular calcium in mutant T cells unlike in wild-type cells
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immune system
• thymocytes fail to mature beyond the double positive stage
|
• no single positive T cells are seen in spleen and lymph nodes
|
• antibody induced co-cross-linking of surface T cell receptors and CD4 failed to mobilize intracellular calcium in mutant T cells unlike in wild-type cells
|
endocrine/exocrine glands