All Phenotypes C1galt1c1<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

C1galt1c1⁺
wild type
MGI:3526584

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	C1galt1c1^tm1.2Rdcu/C1galt1c1⁺	involves: 129S6/SvEvTac * C57BL/6J * FVB/N	MGI:4459547

Allelic Composition	C1galt1c1^tm1.2Rdcu/C1galt1c1⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C1galt1c1^tm1.2Rdcu mutation (0 available); any C1galt1c1 mutation (16 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:160290 )

• remaining mice die postnatally

embryonic lethality during organogenesis, incomplete penetrance ( J:160290 )

• 7 of 25 mice die between E10.5 and E12.5

cardiovascular system

abnormal blood vessel morphology ( J:160290 )

• 3 of 6 mice that survive to E14.5 exhibit disorganized vascular systems compared with wild-type mice

hemorrhage ( J:160290 )

• between E10.5 and E12.5, 7 of 25 mice exhibit hemorrhaging unlike wild-type mice

• 3 of 6 mice that survive to E14.5 exhibit hemorrhaging unlike wild-type mice

growth/size/body

postnatal growth retardation ( J:160290 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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