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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Csrnp1Gt(ROSA)80Sor
gene trapped 80, Philippe Soriano
MGI:3526868
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Csrnp1Gt(ROSA)80Sor/Csrnp1Gt(ROSA)80Sor involves: 129S4/SvJaeSor MGI:3717111


Genotype
MGI:3717111
hm1
Allelic
Composition
Csrnp1Gt(ROSA)80Sor/Csrnp1Gt(ROSA)80Sor
Genetic
Background
involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1Gt(ROSA)80Sor mutation (1 available); any Csrnp1 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 18% of mice die by week 2

skeleton
• abnormal neural crest derived and thoracic skeleton
• 38% aof homozygous mice have smaller presphenoid bone processes that are less extended towards the midline
• 38% of homozygous mice have smaller palatine bone processes that are less extended towards the midline
• 15% of mice have sternum defects including asymmetric or additional fusion of ribs and gaps in the sternum
• 18% of mice die by week 2

craniofacial
• 38% aof homozygous mice have smaller presphenoid bone processes that are less extended towards the midline
• irregularities in fusion persist into adulthood
• 38% of homozygous mice have smaller palatine bone processes that are less extended towards the midline

digestive/alimentary system
• irregularities in fusion persist into adulthood
• 38% of homozygous mice have smaller palatine bone processes that are less extended towards the midline

growth/size/body
• irregularities in fusion persist into adulthood
• 38% of homozygous mice have smaller palatine bone processes that are less extended towards the midline





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory