immune system
• activation of granulocytes by TPA is impaired but no increase in spontaneous infections is seen
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neoplasm
• at 11-25 months, 24% of mice develop lung adenocarcinoma compared with 7% of wild-type mice
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hematopoietic system
• activation of granulocytes by TPA is impaired but no increase in spontaneous infections is seen
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respiratory system
• at 11-25 months, 24% of mice develop lung adenocarcinoma compared with 7% of wild-type mice
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