About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apodtm1Bres
targeted mutation 1, Jan L Breslow
MGI:3528149
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apodtm1Bres/Apodtm1Bres B6.129-Apodtm1Bres MGI:5558015
hm2
 		Apodtm1Bres/Apodtm1Bres involves: 129S1/Sv * 129X1/SvJ * Hsd:ICR MGI:3528228


Genotype
MGI:5558015
hm1
Allelic
Composition		 Apodtm1Bres/Apodtm1Bres
Genetic
Background		 B6.129-Apodtm1Bres
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apodtm1Bres mutation (1 available); any Apod mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Increased myocardial infraction size following ischemia in Apodtm1Bres/Apodtm1Bres mice

mortality/aging
increased susceptibility to induced morbidity/mortality ( J:201999 )
• increase in mortality following ischemia (45 min)/reperfusion (~24 h)

cardiovascular system
abnormal response to cardiac infarction ( J:201999 )
• increase in mortality following ischemia (45 min)/reperfusion (~24 h)
increased myocardial infarct size ( J:201999 )
• following ischemia (45 min)/reperfusion (~24 h)

homeostasis/metabolism
abnormal response to cardiac infarction ( J:201999 )
• increase in mortality following ischemia (45 min)/reperfusion (~24 h)
increased myocardial infarct size ( J:201999 )
• following ischemia (45 min)/reperfusion (~24 h)




Genotype
MGI:3528228
hm2
Allelic
Composition		 Apodtm1Bres/Apodtm1Bres
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * Hsd:ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apodtm1Bres mutation (1 available); any Apod mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:95654 )
N
• the hearing threshold at a range of frequencies between 4 and 60 kHz in males at 9 weeks of age was no different from controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory