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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stat2tm1Jdf
targeted mutation 1, J David Farrar
MGI:3528233
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Stat2tm1Jdf/Stat2tm1Jdf
Tg(DO11.10)10Dlo/0 		C.Cg-Stat2tm1Jdf Tg(DO11.10)10Dlo MGI:3529466


Genotype
MGI:3529466
cx1
Allelic
Composition		 Stat2tm1Jdf/Stat2tm1Jdf
Tg(DO11.10)10Dlo/0
Genetic
Background		 C.Cg-Stat2tm1Jdf Tg(DO11.10)10Dlo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat2tm1Jdf mutation (0 available); any Stat2 mutation (39 available)
Tg(DO11.10)10Dlo mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:95855 )
N
• IFN-alpha stimulation does not promote Th1 cell development similar to Stat2 wild-type mice and unlike in humans




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory