Analysis Tools|
Allele Symbol Allele Name Allele ID |
Bag1tm1Msd targeted mutation 1, Michael Sendtner MGI:3528234 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• embryos die around E13.5
|
|
• at E12.5 the liver is hypoplastic with increased levels of apoptosis compared to wild-type littermates
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• lung tumor initiation is reduced by half at 1, 2, and 4 months of age and lung tumor area is reduced by 75% at 4 months of age
• the number of apoptotic cells in the lung adenomas is increased in double mutants compared to littermates that are wild-type for Bag1
|
|
• lung tumor initiation is reduced by half at 1, 2, and 4 months of age and lung tumor area is reduced by 75% at 4 months of age
• the number of apoptotic cells in the lung adenomas is increased in double mutants compared to littermates that are wild-type for Bag1
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
