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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnk2tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3528830
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcnk2tm1Lex/Kcnk2tm1Lex involves: 129 * C57BL/6 MGI:5575487


Genotype
MGI:5575487
hm1
Allelic
Composition		 Kcnk2tm1Lex/Kcnk2tm1Lex
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk2tm1Lex mutation (1 available); any Kcnk2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:210951 )
N
• mice exhibit normal heart rate, blood pressure, pulse wave velocity, peak blood flow velocities, middle cerebral artery endothelium-mediated dilation, NO and cyclooxygenase-dependent components in the basilar arteries, alpha-linolenic acid-induced basilar artery dilation, and alpha-linoleic acid or arachidonic acid increase in whole cell currents in cerebrovascular smooth muscle cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory