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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cntfrtm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3528869
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cntfrtm1Lex/Cntfrtm1Lex involves: 129S/SvEvBrd MGI:5512680
cn2
 		Cntfrtm1Lex/Cntfrtm1Lex involves: 129S/SvEvBrd MGI:5512681


Genotype
MGI:5512680
hm1
Allelic
Composition		 Cntfrtm1Lex/Cntfrtm1Lex
Genetic
Background		 involves: 129S/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntfrtm1Lex mutation (0 available); any Cntfr mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:137159 )
N
• mice exhibit no apparent abnormalities including normal numbers of motor neurons




Genotype
MGI:5512681
cn2
Allelic
Composition		 Cntfrtm1Lex/Cntfrtm1Lex
Genetic
Background		 involves: 129S/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntfrtm1Lex mutation (0 available); any Cntfr mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased motor neuron number ( J:137159 )
• loss of facial motor neurons 4 month after injection of a cre-expressing adenovirus




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory