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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fkbp11Gt(OST298786)Lex
gene trap OST298786, Lexicon Genetics
MGI:3529240
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fkbp11Gt(OST298786)Lex/Fkbp11Gt(OST298786)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609948


Genotype
MGI:3609948
hm1
Allelic
Composition		 Fkbp11Gt(OST298786)Lex/Fkbp11Gt(OST298786)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp11Gt(OST298786)Lex mutation (2 available); any Fkbp11 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased immunoglobulin level ( J:103485 )
• increased response to ovalbumin challenge
increased inflammatory response ( J:103485 )
• increased response to zymosan challenge

skeleton
increased bone mineral content ( J:103485 )
• mean bone mineral content is increased
increased bone mineral density ( J:103485 )
• total bone mineral density is increased

hematopoietic system
increased immunoglobulin level ( J:103485 )
• increased response to ovalbumin challenge




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory