All Phenotypes Arpp21<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Arpp21^tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3529328

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arpp21^tm1Lex/Arpp21^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:3624512

Allelic Composition	Arpp21^tm1Lex/Arpp21^tm1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arpp21^tm1Lex mutation (0 available); any Arpp21 mutation (56 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal channel response ( J:94124 )

• two fold enhancement in the ability of both M1 and D2 receptors to modulate L-type calcium channel currents

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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