All Phenotypes Pomt1<Gt(OST194127)Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pomt1^{Gt(OST194127)Lex}
gene trap OST194127, Lexicon Genetics
MGI:3529694

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pomt1^{Gt(OST194127)Lex}/Pomt1^{Gt(OST194127)Lex}	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609838
ht2	Pomt1^{Gt(OST194127)Lex}/Pomt1⁺	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609840

Allelic Composition	Pomt1^{Gt(OST194127)Lex}/Pomt1^{Gt(OST194127)Lex}
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pomt1^{Gt(OST194127)Lex} mutation (2 available); any Pomt1 mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:103485 )

• no homozygotes are present at weaning, stage of lethality not specified

Allelic Composition	Pomt1^{Gt(OST194127)Lex}/Pomt1⁺
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pomt1^{Gt(OST194127)Lex} mutation (2 available); any Pomt1 mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased vasodilation ( J:103485 )

• ectasia is seen in the veins of the kidneys and liver

hematopoietic system

increased neutrophil cell number ( J:103485 )

• absolute neutrophil count is increased

decreased IgG level ( J:103485 )

• serum IgG1 and IgG2a responses to ovalbumin challenge are decreased

immune system