Phenotypes associated with this allele

• Allele Symbol: Msrb1^{Gt(OST336894)Lex}
• Allele Name: gene trap OST336894, Lexicon Genetics
• Allele ID: MGI:3529701
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Msrb1^Gt(OST336894)Lex/Msrb1^Gt(OST336894)Lex	involves: 129S5/SvEvBrd	MGI:3843185

Genotype
MGI:3843185

hm1

• Allelic Composition: Msrb1^{Gt(OST336894)Lex}/Msrb1^{Gt(OST336894)Lex}
• Genetic Background: involves: 129S5/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:147916 )

N • mice survive beyond 20 months

cellular

oxidative stress ( J:147916 )

• mice exhibit an increase in malondialdehyde and protein carbonyl levels in the liver, kidney, and brain; reduced protein and total thiol levels in the liver and kidneys; reduced glutathione in the liver and kidneys; and elevated levels of methionine sulfoxide residues in the liver and kidneys compared to in wild-type mice