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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Msrb1Gt(OST336894)Lex
gene trap OST336894, Lexicon Genetics
MGI:3529701
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Msrb1Gt(OST336894)Lex/Msrb1Gt(OST336894)Lex involves: 129S5/SvEvBrd MGI:3843185


Genotype
MGI:3843185
hm1
Allelic
Composition
Msrb1Gt(OST336894)Lex/Msrb1Gt(OST336894)Lex
Genetic
Background
involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msrb1Gt(OST336894)Lex mutation (0 available); any Msrb1 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice survive beyond 20 months

cellular
• mice exhibit an increase in malondialdehyde and protein carbonyl levels in the liver, kidney, and brain; reduced protein and total thiol levels in the liver and kidneys; reduced glutathione in the liver and kidneys; and elevated levels of methionine sulfoxide residues in the liver and kidneys compared to in wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory