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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc29a2Gt(OST207791)Lex
gene trap OST207791, Lexicon Genetics
MGI:3529770
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc29a2Gt(OST207791)Lex/Slc29a2Gt(OST207791)Lex involves: 129S5/SvEvBrd MGI:6151076


Genotype
MGI:6151076
hm1
Allelic
Composition		 Slc29a2Gt(OST207791)Lex/Slc29a2Gt(OST207791)Lex
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc29a2Gt(OST207791)Lex mutation (1 available); any Slc29a2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased susceptibility to injury ( J:203572 )
• mice are profoundly protected from acute lung injury (ALI) and ALI-associated alterations in gas exchange with longer survival and increased bronchoalveolar lavage fluid adenosine levels and reduced IL6 levels in lung tissues compared with wild-type mice

immune system
decreased interleukin-6 secretion ( J:203572 )
• in the lungs of mice subjected to acute lung injury

hematopoietic system
hematopoietic system phenotype ( J:244602 )
N
• adenosine uptake in erythrocytes is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory