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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc29a2Gt(OST207791)Lex
gene trap OST207791, Lexicon Genetics
MGI:3529770
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc29a2Gt(OST207791)Lex/Slc29a2Gt(OST207791)Lex involves: 129S5/SvEvBrd MGI:6151076


Genotype
MGI:6151076
hm1
Allelic
Composition
Slc29a2Gt(OST207791)Lex/Slc29a2Gt(OST207791)Lex
Genetic
Background
involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc29a2Gt(OST207791)Lex mutation (1 available); any Slc29a2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice are profoundly protected from acute lung injury (ALI) and ALI-associated alterations in gas exchange with longer survival and increased bronchoalveolar lavage fluid adenosine levels and reduced IL6 levels in lung tissues compared with wild-type mice

immune system
• in the lungs of mice subjected to acute lung injury

hematopoietic system
N
• adenosine uptake in erythrocytes is normal





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory