Phenotypes associated with this allele

• Allele Symbol: Ak2^{Gt(OST495245)Lex}
• Allele Name: gene trap OST495245, Lexicon Genetics
• Allele ID: MGI:3529816
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ak2^Gt(OST495245)Lex/Ak2^Gt(OST495245)Lex	involves: 129S5/SvEvBrd * C57BL/6N	MGI:6711699

Genotype
MGI:6711699

hm1

• Allelic Composition: Ak2^{Gt(OST495245)Lex}/Ak2^{Gt(OST495245)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal mitochondrial morphology ( J:305579 )

• E7.5 embryos show severely disrupted and disorganized mitochondria and cristae ultrastructure

disorganized mitochondrial cristae ( J:305579 )

• E7.5 embryos show disrupted and disorganized cristae ultrastructure

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:305579 )

• lethality around E7.5