Allele Symbol Allele Name Allele ID |
Npm1Gt(OST331547)Lex gene trap OST331547, Lexicon Genetics MGI:3529824 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• a single genotyped homozygous mouse died shortly after birth
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• unlike Npm1tm1Ppp heterozygotes, mice exhibit normal blood counts
• the total number and frequency of methylcellulose colony-forming unit (CFU)-granulocyte/monocyte and CFU-granulocyte/erythrocyte/monocyte/megakaryocyte is normal
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• 1.4-fold
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• hematopoietic stem cells exhibit reduced engraftment potential compared with control cells
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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