Phenotypes associated with this allele

• Allele Symbol: Gje1^Mhdaaey12
• Allele Name: Martin Hrabe de Angelis abnormal eyes 12
• Allele ID: MGI:3529958
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gje1^Mhdaaey12/Gje1^Mhdaaey12	involves: C3HeB/FeJ	MGI:3797648
ht2	Gje1^Mhdaaey12/Gje1^+	C3HeB/FeJ-Gje1^Mhdaaey12/Ieg	MGI:3716889
ht3	Gje1^Mhdaaey12/Gje1^+	involves: C3HeB/FeJ	MGI:3797647

Genotype
MGI:3797648

hm1

• Allelic Composition: Gje1^Mhdaaey12/Gje1^Mhdaaey12
• Genetic Background: involves: C3HeB/FeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:136139 )

• mice exhibit empty lens consisting of only an envelope

• the lens grows together (fuses) with other ocular tissues

abnormal lens development ( J:136139 )

• after lens vesicle formation, lens fibers fail to elongate from the posterior part of the lens and the connections between the lens fibers and the lens epithelium are disrupted

abnormal lens vesicle development ( J:136139 )

• the lens grows together (fuses) with other ocular tissues

abnormal lens fiber morphology ( J:136139 )

• primary lens fibers fail to elongate

small lens ( J:136139 )

microphthalmia ( J:136139 )

abnormal retina morphology ( J:136139 )

• mice exhibit retinal folding and poor differentiation

retina fold ( J:136139 )

Genotype
MGI:3716889

ht2

• Allelic Composition: Gje1^Mhdaaey12/Gje1⁺
• Genetic Background: C3HeB/FeJ-Gje1^Mhdaaey12/Ieg

vision/eye

microphthalmia ( J:86685 )

Genotype
MGI:3797647

ht3

• Allelic Composition: Gje1^Mhdaaey12/Gje1⁺
• Genetic Background: involves: C3HeB/FeJ

vision/eye

increased cornea thickness ( J:136139 )

• mice exhibit corneal thickening

cornea opacity ( J:136139 )

abnormal lens fiber morphology ( J:136139 )

• elongating lens fibers fail to reach the anterior epithelium

polar cataract ( J:136139 )

• mice exhibit polar lens opacity

small lens ( J:136139 )

microphthalmia ( J:136139 )