Phenotypes associated with this allele

• Allele Symbol: Ccnd1^{tm2(Ccnd2)Pisc}
• Allele Name: targeted mutation 2, Piotr Sicinski
• Allele ID: MGI:3530077
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccnd1^tm2(Ccnd2)Pisc/Ccnd1^tm2(Ccnd2)Pisc	involves: 129S4/SvJae	MGI:3576065

Genotype
MGI:3576065

hm1

• Allelic Composition: Ccnd1^{tm2(Ccnd2)Pisc}/Ccnd1^{tm2(Ccnd2)Pisc}
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:95994 )

• when lifted by tails, responded by rapidly retracting their limbs

growth/size/body

decreased body weight ( J:95994 )

• displayed average weights corresponding to 87% of those of wildtype, however, survival rates were similar to wildtype

reproductive system

reproductive system phenotype ( J:95994 )

N • mammary tissue development was normal with mothers able to breast-feed their pups

vision/eye

abnormal eye electrophysiology ( J:95994 )

• displayed a-waves with amplitudes that were 78% of normal values in retinas in response to a pulse of light, however retinal development appeared normal