muscle
• significant reduction of cells in 2-week-old patellaris and Achilles tendon and a decrease of proliferating cells in Achilles, patellaris and metatarsal tendons of the newborn hindlimb, however size of Achilles tendon was not altered, localization and number of endothelial cells was normal in Achilles and patellaris tendons, and vessel density in tendons was unaltered in homozygous females and hemizygous males
• 6 month old Achilles tendon had a greater variation of collagen fibril calibers with a higher proportion of thick fibrils and fibrillar surfaces of tendons were uneven and rough
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skeleton
N |
• homozygous females and hemizygous males showed no size differences, malformations, or signs of contractures of the skeleton and the muscle, thymus, heart, liver, spleen, and lung appeared normal
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• significant reduction of cells in 2-week-old patellaris and Achilles tendon and a decrease of proliferating cells in Achilles, patellaris and metatarsal tendons of the newborn hindlimb, however size of Achilles tendon was not altered, localization and number of endothelial cells was normal in Achilles and patellaris tendons, and vessel density in tendons was unaltered in homozygous females and hemizygous males
• 6 month old Achilles tendon had a greater variation of collagen fibril calibers with a higher proportion of thick fibrils and fibrillar surfaces of tendons were uneven and rough
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vision/eye
N |
• retinas and retinal vasculature of homozygous females and hemizygous males showed no differences from wild-type under normal conditions or after oxygen-induced retinopathy
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