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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdc25aGt(OST186277)Lex
gene trap OST186277, Lexicon Genetics
MGI:3530222
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdc25aGt(OST186277)Lex/Cdc25aGt(OST186277)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609658
ht2
 		Cdc25aGt(OST186277)Lex/Cdc25a+ involves: 129S5/SvEvBrd * C57BL/6J MGI:3609659


Genotype
MGI:3609658
hm1
Allelic
Composition		 Cdc25aGt(OST186277)Lex/Cdc25aGt(OST186277)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdc25aGt(OST186277)Lex mutation (2 available); any Cdc25a mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:103485 )
• timing of lethality not actually specified




Genotype
MGI:3609659
ht2
Allelic
Composition		 Cdc25aGt(OST186277)Lex/Cdc25a+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdc25aGt(OST186277)Lex mutation (2 available); any Cdc25a mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal trabecular bone morphology ( J:103485 )
• male heterozygotes exhibited decreased vertebral trabecular bone volume, number, and thickness




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory