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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc9c1tm1Gar
targeted mutation 1, David L Garbers
MGI:3530647
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc9c1tm1Gar/Slc9c1tm1Gar involves: 129S6/SvEvTac * C57BL/6J MGI:3531312


Genotype
MGI:3531312
hm1
Allelic
Composition		 Slc9c1tm1Gar/Slc9c1tm1Gar
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc9c1tm1Gar mutation (1 available); any Slc9c1 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
asthenozoospermia ( J:87248 )
• sperm are morphologically normal but display little or no forward movement
• incubation with ammonium chloride (to increase pH) or cAMP analogs can improve motility
male infertility ( J:87248 )
• males but not females are infertile
• incubation of sperm with ammonium chloride (to increase pH) or cAMP analogs can partially restore fertility in vitro

cellular
asthenozoospermia ( J:87248 )
• sperm are morphologically normal but display little or no forward movement
• incubation with ammonium chloride (to increase pH) or cAMP analogs can improve motility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory