About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ralbp1Gt(OST359995)Lex
gene trap OST359995, Lexicon Genetics
MGI:3530809
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ralbp1Gt(OST359995)Lex/Ralbp1Gt(OST359995)Lex B6;129S5-Ralbp1Gt(OST359995)Lex/Ieg MGI:5428691
hm2
Ralbp1Gt(OST359995)Lex/Ralbp1Gt(OST359995)Lex involves: 129S5/SvEvBrd * C57BL MGI:3590312
ht3
Ralbp1Gt(OST359995)Lex/Ralbp1+ involves: 129S5/SvEvBrd * C57BL MGI:3590313


Genotype
MGI:5428691
hm1
Allelic
Composition
Ralbp1Gt(OST359995)Lex/Ralbp1Gt(OST359995)Lex
Genetic
Background
B6;129S5-Ralbp1Gt(OST359995)Lex/Ieg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralbp1Gt(OST359995)Lex mutation (2 available); any Ralbp1 mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• decreased exploratory activity
• decreased locomotor activity
• decreased sensitivity to pain




Genotype
MGI:3590312
hm2
Allelic
Composition
Ralbp1Gt(OST359995)Lex/Ralbp1Gt(OST359995)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralbp1Gt(OST359995)Lex mutation (2 available); any Ralbp1 mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• survival after X-ray exposure is significantly shorter for homozygotes compared to heterozygotes and wild-type mice

cellular
• markers of oxidative stress are increased, activities of GSH-linked antioxidant enzymes are decreased, and levels of GSH are increased
• changes are greater in homozygotes than in heterozygotes and changes are greater in males than in females




Genotype
MGI:3590313
ht3
Allelic
Composition
Ralbp1Gt(OST359995)Lex/Ralbp1+
Genetic
Background
involves: 129S5/SvEvBrd * C57BL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralbp1Gt(OST359995)Lex mutation (2 available); any Ralbp1 mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• survival after X-ray exposure is significantly shorter for homozygotes compared to wild-type mice

cellular
• markers of oxidative stress are increased, activities of GSH-linked antioxidant enzymes are decreased, and levels of GSH are increased
• changes are greater in homozygotes than in heterozygotes and changes are greater in males than in females





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory