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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map4k5Gt(OST218153)Lex
gene trap OST218153, Lexicon Genetics
MGI:3530833
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Map4k5Gt(OST218153)Lex/Map4k5Gt(OST218153)Lex B6;129S5-Map4k5Gt(OST218153)Lex/Ieg MGI:5428681


Genotype
MGI:5428681
hm1
Allelic
Composition		 Map4k5Gt(OST218153)Lex/Map4k5Gt(OST218153)Lex
Genetic
Background		 B6;129S5-Map4k5Gt(OST218153)Lex/Ieg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map4k5Gt(OST218153)Lex mutation (2 available); any Map4k5 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hypoalgesia ( J:82809 )
• homozygous mutant mice exhibit decreased sensitivity to acute pain

hematopoietic system
increased CD4-positive, alpha-beta T cell number ( J:82809 )
• homozygous mutant mice exhibit increased percentage of peripheral blood CD4+ cells
increased IgG1 level ( J:82809 )
• homozygous mutant mice exhibit increased serum IgG1

immune system
increased CD4-positive, alpha-beta T cell number ( J:82809 )
• homozygous mutant mice exhibit increased percentage of peripheral blood CD4+ cells
increased IgG1 level ( J:82809 )
• homozygous mutant mice exhibit increased serum IgG1




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory