All Phenotypes Sle16<129S6/SvEvTac> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sle16^{129S6/SvEvTac}
129S6/SvEvTac
MGI:3531336

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sle16^{129S6/SvEvTac}/Sle16^{129S6/SvEvTac}	B6.129-Sle16^{129S6/SvEvTac}	MGI:3714794
cx2	C1qa^tm1Mjw/C1qa^tm1Mjw Sle16^{129S6/SvEvTac}/Sle16^{129S6/SvEvTac}	involves: 129S/SvEv * 129X1/Sv * C57BL/6	MGI:3701667
cx3	C1qa^tm1Mjw/C1qa^tm1Mjw Sle16^{129S6/SvEvTac}/Sle16^C57BL/6	involves: 129S/SvEv * 129X1/Sv * C57BL/6	MGI:3701668
ot4	Sle16^{129S6/SvEvTac}/?	involves: 129X1/Sv * C57BL/6	MGI:3531341

Allelic Composition	Sle16^{129S6/SvEvTac}/Sle16^{129S6/SvEvTac}
Genetic Background	B6.129-Sle16^{129S6/SvEvTac}

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to systemic lupus erythematosus ( J:122132 )

increased autoantibody level ( J:122132 )

Allelic Composition	C1qa^tm1Mjw/C1qa^tm1Mjw Sle16^{129S6/SvEvTac}/Sle16^{129S6/SvEvTac}
Genetic Background	involves: 129S/SvEv * 129X1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C1qa^tm1Mjw mutation (1 available); any C1qa mutation (24 available)
Sle16^{129S6/SvEvTac} mutation (0 available); any Sle16 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to systemic lupus erythematosus ( J:118645 )

increased anti-nuclear antigen antibody level ( J:118645 )

increased anti-chromatin antibody level ( J:118645 )

increased anti-double stranded DNA antibody level ( J:118645 )

increased anti-single stranded DNA antibody level ( J:118645 )

Allelic Composition	C1qa^tm1Mjw/C1qa^tm1Mjw Sle16^{129S6/SvEvTac}/Sle16^C57BL/6
Genetic Background	involves: 129S/SvEv * 129X1/Sv * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to systemic lupus erythematosus ( J:118645 )

increased anti-nuclear antigen antibody level ( J:118645 )

increased anti-chromatin antibody level ( J:118645 )

increased anti-double stranded DNA antibody level ( J:118645 )

increased anti-single stranded DNA antibody level ( J:118645 )

Allelic Composition	Sle16^{129S6/SvEvTac}/?
Genetic Background	involves: 129X1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immune serum protein physiology ( J:93297 )

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