cardiovascular system
N |
• heart rate, diastolic and systolic blood pressure, and pulse pressure tend to be slightly elevated but are within normal limits
|
craniofacial
• the frontal bone is significantly shorter; however the parietal bone is normal
|
• the nasal bone is significantly shorter
|
short snout
(
J:96633
)
growth/size/body
• the nasal bone is significantly shorter
|
short snout
(
J:96633
)
• first seen at about 1 month of age but transgenics tend to eat slightly more than wild-type mice
|
• when placed on a high fat diet male and to a lesser extent female transgenic gain less weight and adipose tissue than wild-type mice
|
homeostasis/metabolism
• when placed on a high fat diet male and to a lesser extent female transgenic gain less weight and adipose tissue than wild-type mice
|
• increased 1.5- to 2-fold in both males and females; however, TSH levels were not increased
|
• increased 1.5- to 2-fold in both males and females; however, TSH levels were not increased
|
• transgenics consume more oxygen per unit body weight compared to wild-type mice on either a normal or high fat diet
|
skeleton
• the frontal bone is significantly shorter; however the parietal bone is normal
|
• the nasal bone is significantly shorter
|
respiratory system
• the nasal bone is significantly shorter
|