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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Efnb2tm6Kln
targeted mutation 6, Rudiger Klein
MGI:3573786
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Efnb2tm6Kln/Efnb2tm6Kln involves: C57BL/6 MGI:3574332


Genotype
MGI:3574332
hm1
Allelic
Composition		 Efnb2tm6Kln/Efnb2tm6Kln
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm6Kln mutation (0 available); any Efnb2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymph circulation ( J:95885 )
• much milder defect in lymphatic drainage than in homozygous Efnb2tm6.1Kln mutants
abnormal lymphatic vessel morphology ( J:95885 )
• much milder defect in the remodeling of the lymphatic capillary plexus into the formation of the hierarchical network than in homozygous Efnb2tm6.1Kln mutants

cardiovascular system
abnormal lymph circulation ( J:95885 )
• much milder defect in lymphatic drainage than in homozygous Efnb2tm6.1Kln mutants




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory