All Phenotypes Edn1<tm1.1Ywa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Edn1^tm1.1Ywa
targeted mutation 1.1, Masashi Yanagisawa
MGI:3573945

Summary

2 genotypes

Allelic Composition	Edn1^tm1.1Ywa/Edn1^tm1.1Ywa
Genetic Background	involves: 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edn1^tm1.1Ywa mutation (0 available); any Edn1 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die shortly after birth

cardiovascular system

• authors state that mice exhibit identical cardiac defects as reported in Edn1^tm1Utj and Ednra^tm1Ywa homozygotes

craniofacial

abnormal craniofacial morphology ( J:196635 )

• authors state that mice exhibit identical craniofacial defects as reported in Edn1^tm1Utj and Ednra^tm1Ywa homozygotes

Allelic Composition	Edn1^tm1.1Ywa/Edn1⁺
Genetic Background	involves: 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edn1^tm1.1Ywa mutation (0 available); any Edn1 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:196635 )

N	• mice exhibit normal blood pressure and response to vasoactive substances (NG-nitro-L-arginine methyl ester or captopril)

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