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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx
deletion, Chr 2, Gregory A Cox 1
MGI:3574364
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx/Del(2Hoxd8,Hoxd9-Hoxd13)1Cx involves: NZW/LacJ MGI:3616443


Genotype
MGI:3616443
hm1
Allelic
Composition
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx/Del(2Hoxd8,Hoxd9-Hoxd13)1Cx
Genetic
Background
involves: NZW/LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx mutation (1 available); any Del(2Hoxd8,Hoxd9-Hoxd13)1Cx mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• complete hindlimb paralysis

nervous system
• reduced dorso-lumbar plexus
• absent peroneal branch from dorso-lumbar plexus
• no dorso-sacral plexus
• 24th and 25th spinal roots transformed to 24th and 25th
• only partial transformation of 23rd and 24th spinal roots to 22nd and 23rd

muscle
• severe atrophy of anterolateral leg compartment muscles





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory