Phenotypes associated with this allele

• Allele Symbol: Tg(Sftpc-Nmyc1/EGFP)1Blh
• Allele Name: transgene insertion 1, Brigid L Hogan
• Allele ID: MGI:3574950
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Sftpc-Nmyc1/EGFP)1Blh/0	involves: C57BL/6 * DBA	MGI:3575014

Genotype
MGI:3575014

tg1

• Allelic Composition: Tg(Sftpc-Nmyc1/EGFP)1Blh/0
• Genetic Background: involves: C57BL/6 * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

abnormal lung development ( J:97215 )

• at E18.5 mutants lungs display more undifferentiated endoderm, a higher number of proliferating cells, and an indistinct boundary at the site of the future bronchioalveolar duct junction

• differentiation of progenitor cells into proximal or distal cell types is reduced

absent pulmonary alveoli ( J:97215 )

• primitive alveoli are absent at E18.5 instead the lings contain many distal epithelial tubules surrounded by abundant mesenchyme