Phenotypes associated with this allele

• Allele Symbol: Hspa1b^tm1Jss
• Allele Name: targeted mutation 1, Jeong-Sun Seo
• Allele ID: MGI:3575001
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hspa1b^tm1Jss/Hspa1b^tm1Jss	involves: C57BL/6	MGI:3576230

Genotype
MGI:3576230

hm1

• Allelic Composition: Hspa1b^tm1Jss/Hspa1b^tm1Jss
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased cellular sensitivity to oxidative stress ( J:97232 )

• osmotic stress reduced cell viability of embryonic fibroblasts isolated from homozygous mice

increased kidney apoptosis ( J:97232 )

• when osmotic stress was applied in vivo, homozygous mice exhibited increased apoptosis in the renal medulla

renal/urinary system

increased kidney apoptosis ( J:97232 )

• when osmotic stress was applied in vivo, homozygous mice exhibited increased apoptosis in the renal medulla