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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Epha7tm1Jf
targeted mutation 1, Jonas Frisen
MGI:3575006
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Epha7tm1Jf/Epha7tm1Jf involves: 129/Sv * C57BL/6 MGI:3575394
hm2
 		Epha7tm1Jf/Epha7tm1Jf Not Specified MGI:3575318


Genotype
MGI:3575394
hm1
Allelic
Composition		 Epha7tm1Jf/Epha7tm1Jf
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epha7tm1Jf mutation (0 available); any Epha7 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain morphology ( J:96025 )
• increased BrdU incorporation in progenitor cells in the lateral ventricle wall and increased proliferation of neural progenitor cells in vitro




Genotype
MGI:3575318
hm2
Allelic
Composition		 Epha7tm1Jf/Epha7tm1Jf
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epha7tm1Jf mutation (0 available); any Epha7 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
anencephaly ( J:77779 )
• 24% of homozygotes display anencephaly




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory