Phenotypes associated with this allele

• Allele Symbol: Cald1^tm1Claw
• Allele Name: targeted mutation 1, C-L Albert Wang
• Allele ID: MGI:3576365
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cald1^tm1Claw/Cald1^tm1Claw	involves: 129X1/SvJ * C57BL/6J	MGI:3576514

Genotype
MGI:3576514

hm1

• Allelic Composition: Cald1^tm1Claw/Cald1^tm1Claw
• Genetic Background: involves: 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:97432 )

• all herniated homozygotes die within 5-7 hours after birth, owing either to starvation or cannibalism, however 30% of homozygotes survive (those that do not develop hernia)

growth/size/body

omphalocele ( J:97432 )

• many homozygotes develop symptoms similar to umbilical hernia, in which the ventral wall failed to close, resulting in protrusion of the intestines and sometimes liver and other organs