All Phenotypes Tg(Rho-icre)1Ck MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Rho-icre)1Ck
transgene insertion 1, Ching-Kang Chen
MGI:3576662

Summary

11 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nampt^tm1Oleo/Nampt^tm1Oleo Tg(Rho-icre)1Ck/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	MGI:6383809
cn2	Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Rho-icre)1Ck/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	MGI:6505487
cn3	Pdcl^tm1.1Bmw/Pdcl^tm1.1Bmw Tg(Rho-icre)1Ck/0	involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL	MGI:5516349
cn4	Ift172^tm1.1Rama/Ift172^tm1.1Rama Tg(Rho-icre)1Ck/0	involves: 129X1/SvJ * C57BL/6 * SJL	MGI:6383402
cn5	Emc1^em1Xjz/Emc1^em1Xjz Tg(Rho-icre)1Ck/0	involves: C57BL/6 * C57BL/6J * SJL	MGI:7611972
cn6	Nudc^{tm1c(KOMP)Mbp}/Nudc^{tm1c(KOMP)Mbp} Tg(Rho-icre)1Ck/0	involves: C57BL/6 * C57BL/6N * SJL	MGI:7618543
cn7	Nmnat1^{tm1c(EUCOMM)Wtsi}/Nmnat1^{tm1c(EUCOMM)Wtsi} Tg(Rho-icre)1Ck/0	involves: C57BL/6J * C57BL/6N * SJL	MGI:6272877
cn8	Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu} Tg(Rho-icre)1Ck/0	involves: C57BL/6J * C57BL/6N * SJL	MGI:6386321
cn9	Nrf1^{tm1c(KOMP)Wtsi}/Nrf1^{tm1c(KOMP)Wtsi} Tg(Rho-icre)1Ck/0	involves: C57BL/6N * SJL	MGI:6383436
cn10	Elovl4^tm3Kzh/Elovl4^tm3Kzh Tg(Rho-icre)1Ck/?	involves: C57BL/6 * SJL	MGI:5492071
cn11	Cetn1^tm1Wbae/Cetn1^tm1Wbae Tg(Rho-icre)1Ck/0	involves: C57BL/6 * SJL	MGI:6361417

Allelic Composition	Nampt^tm1Oleo/Nampt^tm1Oleo Tg(Rho-icre)1Ck/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nampt^tm1Oleo mutation (1 available); any Nampt mutation (93 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

optic nerve atrophy ( J:265592 )

• secondary with pallor by 6 weeks

abnormal retina morphology ( J:265592 )

• rounded and constricted with loss of cristae in the retinal mitochondria by 4 weeks

• cytoplasmic vacuoles containing degenerating organelles including ruptured mitochondria

abnormal photoreceptor inner segment morphology ( J:265592 )

• by 4 weeks

abnormal photoreceptor outer segment morphology ( J:265592 )

• by 4 weeks

retina photoreceptor degeneration ( J:265592 )

• by 6 weeks with massive atrophy of the neurosensory retina and vascular attenuation with pigment mottling

• however, nicotinamide mononucleotide treatment rescued regeneration

retina pigment epithelium atrophy ( J:265592 )

• by 6 weeks

thin retina outer nuclear layer ( J:265592 )

• progressive and almost completely absent by 6 weeks

decreased total retina thickness ( J:265592 )

• by 6 weeks

abnormal cone electrophysiology ( J:265592 )

• reduced b-waves amplitudes by 6 weeks of age

• reduced visual acuity by 6 weeks of age

• however, nicotinamide mononucleotide treatment rescued function

abnormal rod electrophysiology ( J:265592 )

• reduced a-waves amplitudes by 6 weeks of age

• however, nicotinamide mononucleotide treatment rescued function

cellular

abnormal mitochondrial morphology ( J:265592 )

• rounded and constricted with loss of cristae in the retinal mitochondria by 4 weeks

abnormal mitochondrial crista morphology ( J:265592 )

• loss of cristae in the retinal mitochondria by 4 weeks

nervous system

abnormal photoreceptor inner segment morphology ( J:265592 )

• by 4 weeks

abnormal photoreceptor outer segment morphology ( J:265592 )

• by 4 weeks

retina photoreceptor degeneration ( J:265592 )

• by 6 weeks with massive atrophy of the neurosensory retina and vascular attenuation with pigment mottling

• however, nicotinamide mononucleotide treatment rescued regeneration

optic nerve atrophy ( J:265592 )

• secondary with pallor by 6 weeks

pigmentation

retina pigment epithelium atrophy ( J:265592 )

• by 6 weeks

Allelic Composition	Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Rho-icre)1Ck/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrip^tm1.1Pof mutation (0 available); any Atrip mutation (26 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:297493 )

N	• retinas show normal lamination and outer nuclear layer and mice exhibit normal visual acuity at 7 months of age

Allelic Composition	Pdcl^tm1.1Bmw/Pdcl^tm1.1Bmw Tg(Rho-icre)1Ck/0
Genetic Background	involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdcl^tm1.1Bmw mutation (0 available); any Pdcl mutation (23 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal retina photoreceptor morphology ( J:197148 )

short retina rod cell outer segment ( J:197148 )

• about 25% shortening of outer segments relative to controls at 35 days

• the very few rods remaining at 6 months are malformed with almost no outer segment

retina photoreceptor degeneration ( J:197148 )

• progressive photoreceptor degeneration

retina rod cell degeneration ( J:197148 )

• no loss at 1 month

• definite losses at 2 months

• half of nuclei are lost by 3-4 months

• almost all nuclei are lost by 9 months

abnormal eye physiology ( J:197148 )

photosensitivity ( J:197148 )

• reduced response to light flashes

• twelve fold increase in light intensity required for a 1/2 saturating response

abnormal electroretinogram waveform feature ( J:197148 )

• considerable reduction in light sensitivity and response amplitude

• seventeen fold desensitization for the a-wave and a two fold reduction in maximal response

• 25% decrease in response amplitude

• 3.8 fold reduction in signal amplification rate

• substantially decelerated falling phase

decreased visual acuity ( J:197148 )

• 3 fold reduction in visual acuity under dim lighting

• visual acuity is normal under bright lights

delayed dark adaptation ( J:197148 )

• recovery time constant is increased five fold

nervous system

abnormal retina photoreceptor morphology ( J:197148 )

short retina rod cell outer segment ( J:197148 )

• about 25% shortening of outer segments relative to controls at 35 days

• the very few rods remaining at 6 months are malformed with almost no outer segment

retina photoreceptor degeneration ( J:197148 )

• progressive photoreceptor degeneration

retina rod cell degeneration ( J:197148 )

• no loss at 1 month

• definite losses at 2 months

• half of nuclei are lost by 3-4 months

• almost all nuclei are lost by 9 months

homeostasis/metabolism

photosensitivity ( J:197148 )

• reduced response to light flashes

• twelve fold increase in light intensity required for a 1/2 saturating response

Allelic Composition	Ift172^tm1.1Rama/Ift172^tm1.1Rama Tg(Rho-icre)1Ck/0
Genetic Background	involves: 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift172^tm1.1Rama mutation (1 available); any Ift172 mutation (75 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal photoreceptor outer segment morphology ( J:262800 )

abnormal photoreceptor outer segment disc membrane morphology ( J:262800 )

• outer segment disc disorganization and accumulation of extracellular debris is seen at P25 and P28

short photoreceptor outer segment ( J:262800 )

• mice show a shortening of the outer segment length at 1 month of age

disorganized photoreceptor outer segment ( J:262800 )

• at P31, the outer segments are disorganized and appear to lose the connection with the axoneme and innersegment of the photoreceptor cell

• mice show mislocalization of photoreceptor outer segment proteins

photoreceptor outer segment degeneration ( J:262800 )

• outer segments are fully degenerated by P31

retina outer nuclear layer degeneration ( J:262800 )

• mice show thinning of the outer nuclear layer at 1 month, with a 38% reduction, and a complete degeneration by 2 months

retina degeneration ( J:262800 )

• mice exhibit rapid retinal degeneration showing decreased neural retinal thickness due to thinning and eventual loss of the outer nuclear layer by 2 months of age

• however, mice do not show retinal cysts

abnormal electroretinogram waveform feature ( J:262800 )

• mixed rod/cone responses are reduced by half at 1 month of age

• by 2 months of age, the ERG is severely affected or undetectable across the stimulus conditions

decreased b-wave amplitude ( J:262800 )

• mice show an 84% reduction of rod-driven b-wave amplitude at 0.01 cd/m² light stimulus after dark adaptation at 1 month of age

• mice show a reduction in cone-isolated b-wave amplitude at 20 cd/m² light stimulus after light adaptation at 2 months of age, indicating secondary cone degeneration

nervous system

abnormal photoreceptor outer segment morphology ( J:262800 )

abnormal photoreceptor outer segment disc membrane morphology ( J:262800 )

• outer segment disc disorganization and accumulation of extracellular debris is seen at P25 and P28

short photoreceptor outer segment ( J:262800 )

• mice show a shortening of the outer segment length at 1 month of age

disorganized photoreceptor outer segment ( J:262800 )

• at P31, the outer segments are disorganized and appear to lose the connection with the axoneme and innersegment of the photoreceptor cell

• mice show mislocalization of photoreceptor outer segment proteins

photoreceptor outer segment degeneration ( J:262800 )

• outer segments are fully degenerated by P31

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
retinal degeneration		DOID:8466		J:262800

Allelic Composition	Emc1^em1Xjz/Emc1^em1Xjz Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emc1^em1Xjz mutation (0 available); any Emc1 mutation (56 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

increased retina apoptosis ( J:345827 )

• at 2 months of age mainly in the outer nuclear layer

thin retina outer nuclear layer ( J:345827 )

• at 2 months of age

abnormal retina photoreceptor layer morphology ( J:345827 )

• decreased thickness of the photoreceptor segment at 2 months of age

abnormal photoreceptor outer segment morphology ( J:345827 )

• mislocalized rhodopsin at 2 months of age

short photoreceptor outer segment ( J:345827 )

• at 2 months of age

disorganized photoreceptor outer segment ( J:345827 )

• at 2 months of age

photoreceptor outer segment degeneration ( J:345827 )

• most signs of degeneration at 2 months of age are seen in the outer segments

retina photoreceptor degeneration ( J:345827 )

• progressive degeneration with almost complete loss at 3.5 months of age

decreased a-wave amplitude ( J:345827 )

• at both the 3.0 and 10.0 cd s*m-2 flash intensity

decreased b-wave amplitude ( J:345827 )

• at both the 3.0 and 10.0 cd s*m-2 flash intensity

abnormal rod electrophysiology ( J:345827 )

• reduced scotopic response with both the amplitude of the a-wave and b-wave reduced at both the 3.0 and 10.0 cd s*m-2 flash intensity

nervous system

abnormal photoreceptor outer segment morphology ( J:345827 )

• mislocalized rhodopsin at 2 months of age

short photoreceptor outer segment ( J:345827 )

• at 2 months of age

disorganized photoreceptor outer segment ( J:345827 )

• at 2 months of age

photoreceptor outer segment degeneration ( J:345827 )

• most signs of degeneration at 2 months of age are seen in the outer segments

retina photoreceptor degeneration ( J:345827 )

• progressive degeneration with almost complete loss at 3.5 months of age

cellular

increased retina apoptosis ( J:345827 )

• at 2 months of age mainly in the outer nuclear layer

Allelic Composition	Nudc^{tm1c(KOMP)Mbp}/Nudc^{tm1c(KOMP)Mbp} Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6 * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nudc^{tm1c(KOMP)Mbp} mutation (0 available); any Nudc mutation (21 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

increased retina apoptosis ( J:346299 )

• by 3 weeks of age, apoptosis in the outer nuclear layer is detected

abnormal photoreceptor inner segment morphology ( J:346299 )

• mitochondria within the inner segment are smaller and are mislocalized, being dispersed within the inner segment instead of being located against the plasma membrane

• rhodopsin is retained in the outer nuclear layer and inner segment in 2- and 3-week old mice, indicating that it is not normally transported to the outer segment

abnormal photoreceptor outer segment morphology ( J:346299 )

• loss of photoreceptors is concurrent with loss of rod outer segment proteins, including rhodopsin and transducin

abnormal photoreceptor outer segment disc membrane morphology ( J:346299 )

• rod photoreceptors show regions of abnormal disc overgrowth or occasional dysmorphic disc membranes

abnormal retina rod cell morphology ( J:346299 )

• rod cells frequently have an extended periciliary ridge and in some cases, the discs in the retina grow parallel to the axoneme

retina rod cell degeneration ( J:346299 )

• 40% loss of rods is seen at 3 weeks of age and at 6 weeks of age, rod photoreceptors are completely degenerated, with no detectable outer segment region

abnormal retina outer nuclear layer morphology ( J:346299 )

• rhodopsin is retained in the outer nuclear layer and inner segment in 2- and 3-week old mice, indicating that it is not normally transported to the outer segment

retina outer nuclear layer degeneration ( J:346299 )

• 40% loss of outer nuclear layer nuclei at 3 weeks of age, indicating early rod photoreceptor degeneration

decreased total retina thickness ( J:346299 )

• thinning retina at 3 weeks of age

• however, the remaining outer segments appear normal

abnormal electroretinogram waveform feature ( J:346299 )

decreased a-wave implicit time ( J:346299 )

• while a-wave implicit time is not affected at 3 weeks of age, by 6 weeks of age it is reduced in both the scotopic and photopic conditions

decreased a-wave amplitude ( J:346299 )

• scotopic a-wave amplitude is diminished and photopic a-wave amplitude is reduced at 3 weeks of age, however a-wave implicit times are not affected

• at 6 weeks of age, mice show no response in the scotopic condition and the a-wave is diminished and show a decrease in photopic a-wave amplitude

decreased b-wave amplitude ( J:346299 )

• scotopic b-wave amplitude is diminished and photopic b-wave amplitude is reduced at 3 weeks of age, however b-wave implicit times are not affected

• at 6 weeks of age, mice show no response in the scotopic condition and the b-wave is diminished and show a decrease in photopic a-wave amplitude

nervous system

increased microglial cell activation ( J:346299 )

• microglial activity is increased and microglia are also seen in the inner segment and in the retinal ganglion cell layer, while normal location of microglia is in the plexiform layers

• retinas show an increase in GFAP-positive Muller glial processes extending up through the retina

abnormal photoreceptor inner segment morphology ( J:346299 )

• mitochondria within the inner segment are smaller and are mislocalized, being dispersed within the inner segment instead of being located against the plasma membrane

• rhodopsin is retained in the outer nuclear layer and inner segment in 2- and 3-week old mice, indicating that it is not normally transported to the outer segment

abnormal photoreceptor outer segment morphology ( J:346299 )

• loss of photoreceptors is concurrent with loss of rod outer segment proteins, including rhodopsin and transducin

abnormal photoreceptor outer segment disc membrane morphology ( J:346299 )

• rod photoreceptors show regions of abnormal disc overgrowth or occasional dysmorphic disc membranes

abnormal retina rod cell morphology ( J:346299 )

• rod cells frequently have an extended periciliary ridge and in some cases, the discs in the retina grow parallel to the axoneme

retina rod cell degeneration ( J:346299 )

• 40% loss of rods is seen at 3 weeks of age and at 6 weeks of age, rod photoreceptors are completely degenerated, with no detectable outer segment region

cellular

increased retina apoptosis ( J:346299 )

• by 3 weeks of age, apoptosis in the outer nuclear layer is detected

hematopoietic system

increased microglial cell activation ( J:346299 )

• microglial activity is increased and microglia are also seen in the inner segment and in the retinal ganglion cell layer, while normal location of microglia is in the plexiform layers

• retinas show an increase in GFAP-positive Muller glial processes extending up through the retina

immune system

increased microglial cell activation ( J:346299 )

• microglial activity is increased and microglia are also seen in the inner segment and in the retinal ganglion cell layer, while normal location of microglia is in the plexiform layers

• retinas show an increase in GFAP-positive Muller glial processes extending up through the retina

Allelic Composition	Nmnat1^{tm1c(EUCOMM)Wtsi}/Nmnat1^{tm1c(EUCOMM)Wtsi} Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6J * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nmnat1^{tm1c(EUCOMM)Wtsi} mutation (0 available); any Nmnat1 mutation (36 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal retina rod cell outer segment morphology ( J:267630 )

• no rod outer segments are detectable by P15

retina rod cell degeneration ( J:267630 )

• the outer nuclear layer is reduced at P28 but not P7, indicating that most rods are lost

vision/eye

abnormal retina rod cell outer segment morphology ( J:267630 )

• no rod outer segments are detectable by P15

retina rod cell degeneration ( J:267630 )

• the outer nuclear layer is reduced at P28 but not P7, indicating that most rods are lost

retina outer nuclear layer degeneration ( J:267630 )

• the outer nuclear layer is reduced at P28 but not P7, indicating that most rods are lost

retina degeneration ( J:267630 )

Allelic Composition	Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu} Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6J * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arl3^{Gt(EUCJ0159b07)1.1Hmgu} mutation (0 available); any Arl3 mutation (27 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal retina rod cell outer segment morphology ( J:232436 )

• slightly reduced

retina cone cell degeneration ( J:232436 )

• at 2 months

retina rod cell degeneration ( J:232436 )

• at 2 months

thin retina inner nuclear layer ( J:232436 )

• slightly

decreased total retina thickness ( J:232436 )

• progressive, at P15 and further by P50

abnormal cone electrophysiology ( J:232436 )

• begins to decline at 1 month

abnormal rod electrophysiology ( J:232436 )

• reduced a- and b-waves at 1 month

• however, readings at P15 are normal

behavior/neurological

abnormal optokinetic reflex ( J:232436 )

• extinct at 2 months

• however, optokinetic response at 1 month is normal

nervous system

abnormal retina rod cell outer segment morphology ( J:232436 )

• slightly reduced

retina cone cell degeneration ( J:232436 )

• at 2 months

retina rod cell degeneration ( J:232436 )

• at 2 months

Allelic Composition	Nrf1^{tm1c(KOMP)Wtsi}/Nrf1^{tm1c(KOMP)Wtsi} Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrf1^{tm1c(KOMP)Wtsi} mutation (0 available); any Nrf1 mutation (70 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

decreased retina cone cell number ( J:267504 )

• at 8 weeks of age

decreased retina rod cell number ( J:267504 )

• at 8 weeks of age

short photoreceptor inner segment ( J:267504 )

• at 6 weeks of age

short photoreceptor outer segment ( J:267504 )

• at 6 weeks of age

retina rod cell degeneration ( J:267504 )

thin retina outer nuclear layer ( J:267504 )

• starting at 8 weeks of age and almost disappeared at 5 months

abnormal cone electrophysiology ( J:267504 )

• b-wave amplitudes decline at 8 weeks and are undetectable beyond 10 weeks of age

abnormal rod electrophysiology ( J:267504 )

• a-wave amplitudes decline at 6 weeks and are completely diminished at 3 months of age

cellular

abnormal mitochondrial morphology ( J:267504 )

• more rounded shape in rod cells with clustering of mitochondria near the outer limiting membrane unlike in wild-type cells

decreased mitochondrial size ( J:267504 )

• in rod cells

increased mitochondrial number ( J:267504 )

• 2.5 times in rod cells of the inner segment

abnormal mitochondrial physiology ( J:267504 )

• reduced COX activity in rod cells of the inner segment

nervous system

decreased retina cone cell number ( J:267504 )

• at 8 weeks of age

decreased retina rod cell number ( J:267504 )

• at 8 weeks of age

short photoreceptor inner segment ( J:267504 )

• at 6 weeks of age

short photoreceptor outer segment ( J:267504 )

• at 6 weeks of age

retina rod cell degeneration ( J:267504 )

Allelic Composition	Elovl4^tm3Kzh/Elovl4^tm3Kzh Tg(Rho-icre)1Ck/?
Genetic Background	involves: C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elovl4^tm3Kzh mutation (0 available); any Elovl4 mutation (36 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:194246 )

N	• no abnormalities • normal ERG and normal visual performance up to 6.5 months

abnormal retina rod cell morphology ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods

homeostasis/metabolism

decreased unsaturated fatty acids level ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods

• decreases by 97.6%

nervous system

abnormal retina rod cell morphology ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods

Allelic Composition	Cetn1^tm1Wbae/Cetn1^tm1Wbae Tg(Rho-icre)1Ck/0
Genetic Background	involves: C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cetn1^tm1Wbae mutation (0 available); any Cetn1 mutation (2 available)
Tg(Rho-icre)1Ck mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:276829 )

N	• electroretinograms show no significant differences in scotopic ERG a-wave amplitudes relative to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24