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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Raxtm1.2Lwd
targeted mutation 1.2, Mark Lewandoski
MGI:3576779
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Raxtm1.2Lwd/Raxtm1.2Lwd involves: 129S1/Sv * C57BL/6 MGI:3578775


Genotype
MGI:3578775
hm1
Allelic
Composition
Raxtm1.2Lwd/Raxtm1.2Lwd
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Raxtm1.2Lwd mutation (0 available); any Rax mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

vision/eye
• fail to form ocular tissue

nervous system
• delayed anterior neural tube closure

craniofacial
• optic pit fails to form
• display a spectrum of craniofacial defects including severe ventral and dorsal clefts of the palate

digestive/alimentary system
• display a spectrum of craniofacial defects including severe ventral and dorsal clefts of the palate

embryo
• delayed anterior neural tube closure

growth/size/body
• display a spectrum of craniofacial defects including severe ventral and dorsal clefts of the palate





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory