Analysis Tools|
Allele Symbol Allele Name Allele ID |
Myh11tm1Peri targeted mutation 1, Muthu Periasamy MGI:3576856 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• bladder smooth muscle exhibited reduced rate and extent of tension development/force generation in response to increasing KCl concentrations compared to wildtype
• mesenteric vessels under KCl depolarization contracted at a slower rate (decreased velocity of shortening) than in wildtype
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• lower rate of bronchoconstriction during the initial 4 seconds in response to methacholine
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• the time to peak baseline airway resistance (RAW) was significantly longer than in widl-type in response to methacholine
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• lower rate of bronchoconstriction during the initial 4 seconds in response to methacholine
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• bladder smooth muscle exhibited reduced rate and extent of tension development/force generation in response to increasing KCl concentrations compared to wildtype
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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