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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Birc2tm1Jda
targeted mutation 1, Jonathan D Ashwell
MGI:3576924
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Birc2tm1Jda/Birc2tm1Jda B6.129P2-Birc2tm1Jda MGI:3583198


Genotype
MGI:3583198
hm1
Allelic
Composition
Birc2tm1Jda/Birc2tm1Jda
Genetic
Background
B6.129P2-Birc2tm1Jda
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1Jda mutation (0 available); any Birc2 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• exhibited a modest reduction in the number of lymphocytes and had increased levels of Birc3 protein, however observed no obvious physical or behavioral abnormalities, no differences in the distribution of thymocytes, had normal T cell activation, were not sensitized to proapoptotic stimuli and had normal life spans

hematopoietic system
• exhibited a modest reduction in the number of lymphocytes and had increased levels of Birc3 protein, however observed no obvious physical or behavioral abnormalities, no differences in the distribution of thymocytes, had normal T cell activation, were not sensitized to proapoptotic stimuli and had normal life spans





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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory