Phenotypes associated with this allele

• Allele Symbol: Myo5a^d-l31J
• Allele Name: dilute lethal 31 Jackson
• Allele ID: MGI:3577027
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo5a^d-l31J/Myo5a^d-l31J	involves: A.B6-Tyr^+	MGI:3577030

Genotype
MGI:3577030

hm1

• Allelic Composition: Myo5a^d-l31J/Myo5a^d-l31J
• Genetic Background: involves: A.B6-Tyr⁺

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:87349 )

• mice are fragile and usually die by or before 5 weeks of age

behavior/neurological

impaired balance ( J:87349 )

• mice intermittently lean to the side, fall over, but are able to regain their walking position

abnormal gait ( J:87349 )

• impaired hind limb movements

• they show 'hot-foot' like behavior of one or both limbs

growth/size/body

decreased body size ( J:87349 )

• animals are small

pigmentation

abnormal coat/hair pigmentation ( J:87349 )

• mice exhibit a non-agouti grey coat color that appears to result from a non-agouti grey allele that is known to exist in heterozygotes for the dilute-lethal allele of Myo5a, and becomes apparent in the presence of the agouti dilute allele, carried by the female NMF244

integument

abnormal coat/hair pigmentation ( J:87349 )

• mice exhibit a non-agouti grey coat color that appears to result from a non-agouti grey allele that is known to exist in heterozygotes for the dilute-lethal allele of Myo5a, and becomes apparent in the presence of the agouti dilute allele, carried by the female NMF244