About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Crebbptm1Pkb
targeted mutation 1, Paul K Brindle
MGI:3578129
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Crebbptm1Pkb/Crebbptm1Pkb involves: 129P2/OlaHsd * C57BL/6 MGI:3578234


Genotype
MGI:3578234
hm1
Allelic
Composition		 Crebbptm1Pkb/Crebbptm1Pkb
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crebbptm1Pkb mutation (2 available); any Crebbp mutation (100 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:98329 )
• about 40% lethality before weaning due to unknown causes, survivors are viable

hematopoietic system
decreased thymocyte number ( J:98329 )
• slight reduction in numbers

growth/size/body
decreased body size ( J:98329 )
• body size was reduced at 4 weeks of age

immune system
decreased thymocyte number ( J:98329 )
• slight reduction in numbers

endocrine/exocrine glands
decreased thymocyte number ( J:98329 )
• slight reduction in numbers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory