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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp36l2tm1Pjb
targeted mutation 1, Perry J Blackshear
MGI:3578661
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfp36l2tm1Pjb/Zfp36l2tm1Pjb either: B6NTac.129-Zfp36l2tm1Pjb or (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ) MGI:3578922


Genotype
MGI:3578922
hm1
Allelic
Composition		 Zfp36l2tm1Pjb/Zfp36l2tm1Pjb
Genetic
Background		 either: B6NTac.129-Zfp36l2tm1Pjb or (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp36l2tm1Pjb mutation (0 available); any Zfp36l2 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
female infertility ( J:98334 )
• females but not males are infertile
• fertilization occurs but embryos arrest at the 2-cell stage
• homozygous females have normal reproductive tract morphology, estrous cycles, and mating behavior, and can carry a pregnancy to term when fertilized embryos are implanted or wild-type ovaries are transplanted




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory