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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tnfrsf19tm1Shmi
targeted mutation 1, Sha Mi
MGI:3579138
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tnfrsf19tm1Shmi/Tnfrsf19tm1Shmi involves: 129/Sv * C57BL/6 MGI:3579519


Genotype
MGI:3579519
hm1
Allelic
Composition		 Tnfrsf19tm1Shmi/Tnfrsf19tm1Shmi
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf19tm1Shmi mutation (0 available); any Tnfrsf19 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron physiology ( J:98433 )
• P7 CG and dorsal root ganglion neurons showed longer neurite outgrowth when cultured on inhibitory myelin substances, indicating decreased inhibition by myelin-associated inhibitor factors, however exhibited no obvious physical abnormalities or alterations in behavior, locomotion or fecundity

homeostasis/metabolism
abnormal response/metabolism to endogenous compounds ( J:98433 )
• P7 CG and dorsal root ganglion neurons showed longer neurite outgrowth when cultured on myelin, Nogo-66 or oligodendrocyte-myelin glycoprotein, indicating decreased inhibition by myelin-associated inhibitor factors




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory