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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mtv2a
mammary tumor virus locus 2, present
MGI:3579297
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mtv2a/Mtv2a DDD.GR-Mtv2a MGI:3626069


Genotype
MGI:3626069
hm1
Allelic
Composition
Mtv2a/Mtv2a
Genetic
Background
DDD.GR-Mtv2a
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtv2a mutation (5 available); any Mtv2 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mammary tumors develop in 70-85% of breeders by approximately 7 months of age
• using the Dunn classification system, 47% of tumors are identified as pale cell, the remaining tumors are classified as Type A+B or type P
• mammary tumors develop in 58% of virgin females by approximately 10 months of age
• using the Dunn classification system 65% of tumors are identified as type A+B, the remaining tumors are classified as pale cell or type P

endocrine/exocrine glands
• mice that do not develop palpable tumors exhibit tumorous lesions or hyperplastic nodules at one year
• mammary tumors develop in 70-85% of breeders by approximately 7 months of age
• using the Dunn classification system, 47% of tumors are identified as pale cell, the remaining tumors are classified as Type A+B or type P
• mammary tumors develop in 58% of virgin females by approximately 10 months of age
• using the Dunn classification system 65% of tumors are identified as type A+B, the remaining tumors are classified as pale cell or type P

integument
• mice that do not develop palpable tumors exhibit tumorous lesions or hyperplastic nodules at one year
• mammary tumors develop in 70-85% of breeders by approximately 7 months of age
• using the Dunn classification system, 47% of tumors are identified as pale cell, the remaining tumors are classified as Type A+B or type P
• mammary tumors develop in 58% of virgin females by approximately 10 months of age
• using the Dunn classification system 65% of tumors are identified as type A+B, the remaining tumors are classified as pale cell or type P





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory