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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(MGS1-19375/CFP)2R9Rwb
transgene insertion 2R9, Robert W Burgess
MGI:3579426
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(APPswe,PSEN1dE9)85Dbo/?
Tg(MGS1-19375/CFP)2R9Rwb/? 		involves: C3H * C57BL/6 * C57BL/6J MGI:5692162


Genotype
MGI:5692162
cx1
Allelic
Composition		 Tg(APPswe,PSEN1dE9)85Dbo/?
Tg(MGS1-19375/CFP)2R9Rwb/?
Genetic
Background		 involves: C3H * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APPswe,PSEN1dE9)85Dbo mutation (6 available)
Tg(MGS1-19375/CFP)2R9Rwb mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:220073 )
• decreased levels of both amyloid beta-40 and -42
• mostly insoluble forms are reduced
• decrease is significant in males but not females

homeostasis/metabolism
amyloid beta deposits ( J:220073 )
• decreased levels of both amyloid beta-40 and -42
• mostly insoluble forms are reduced
• decrease is significant in males but not females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory