All Phenotypes Gabrg2<tm2Geh> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gabrg2^tm2Geh
targeted mutation 2, Gregg E Homanics
MGI:3579440

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gabrg2^tm2Geh/Gabrg2^tm2Geh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3582969

Allelic Composition	Gabrg2^tm2Geh/Gabrg2^tm2Geh
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrg2^tm2Geh mutation (0 available); any Gabrg2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased anxiety-related response ( J:98560 )

• in the elevated plus maze, had a 74% reduction in open arm entries and an 83% reduction in time on open arms and in the forced novelty expoloration test, had a 28% reduction in locomotor activity, indicating increased anxiety-like behavior, however showed normal hypnotic responses to benzodiazepine site ligands and other sedative/hypnotic drugs tested

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24