Phenotypes associated with this allele

• Allele Symbol: L3mbtl3^tm1Tmiy
• Allele Name: targeted mutation 1, Toru Miyazaki
• Allele ID: MGI:3579468
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	L3mbtl3^tm1Tmiy/L3mbtl3^tm1Tmiy	Not Specified	MGI:3580779

Genotype
MGI:3580779

hm1

• Allelic Composition: L3mbtl3^tm1Tmiy/L3mbtl3^tm1Tmiy
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:98498 )

• died during a late embryonic stage between E17.5 and E19.5

hematopoietic system

abnormal definitive hematopoiesis ( J:98498 )

• myeloid progenitor cells exhibit a maturational deficiency but maintain normal proliferative activities, resulting in decrease in mature myeloid lineage cells in fetal liver

anemia ( J:98498 )

• a marked decrease of mature myeloid blood cells due to myeloid progenitor cells maturational deficiency