Phenotypes associated with this allele

• Allele Symbol: Eomes^tm1Jrt
• Allele Name: targeted mutation 1, Janet Rossant
• Allele ID: MGI:3579497
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eomes^tm1Jrt/Eomes^tm1Jrt	either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)	MGI:3580004

Genotype
MGI:3580004

hm1

• Allelic Composition: Eomes^tm1Jrt/Eomes^tm1Jrt
• Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:98502 )

embryo

embryonic growth arrest ( J:98502 )

• after 96 hours in culture embryos remain as expanded blastocysts

absent trophoblast giant cells ( J:98502 )

• after 120 hours in culture, markers for differentiated trophoblast giant cells are undetectable

absent trophectoderm ( J:98502 )

• no trophoectoderm outgrowth is formed

reproductive system

failure of embryo implantation ( J:98502 )

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