mortality/aging
• start to die from E10 to E11.5
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cardiovascular system
• veins and arteries were fused
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• embryos showed pericardium effusion
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embryo
• embryos fail to turn
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• embryos are growth retarded
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• yolk sac exhibited defects in angiogenesis, with no large blood vessels
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growth/size/body
• embryos are growth retarded
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homeostasis/metabolism
• embryos showed pericardium effusion
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